BREAST CANCER

BREAST CANCER

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Breast cancer is a type of cancer that forms in the cells of the breasts. It primarily affects women but can also occur in men, although it is much less common. Breast cancer typically starts in the milk ducts or the lobules, which are the glands that produce milk.

Risk factors for breast cancer include age (the risk increases with age), a family history of breast cancer, certain genetic mutations (such as BRCA1 and BRCA2), early onset of menstruation or late menopause, hormonal factors, obesity, alcohol consumption, and radiation exposure. However, it’s important to note that having one or more risk factors doesn’t necessarily mean a person will develop breast cancer, and individuals without these risk factors can still develop the disease.

Early-stage breast cancer usually doesn’t cause any symptoms. As the cancer progresses, common signs and symptoms may include a lump or thickening in the breast or underarm, changes in the size or shape of the breast, nipple discharge or inversion, skin changes on the breast, such as dimpling or redness, and breast pain. However, these symptoms can also be caused by non-cancerous conditions, so it’s important to consult a healthcare professional for an accurate diagnosis.

Breast cancer can be diagnosed through various methods, including breast exams, imaging tests like mammograms, ultrasounds, or MRIs, and biopsy procedures, which involve removing a sample of tissue from the suspicious area to be examined under a microscope.

Treatment options for breast cancer depend on various factors, such as the stage of cancer, the presence of hormone receptors, and the individual’s overall health. Common treatments include surgery (such as lumpectomy or mastectomy), radiation therapy, chemotherapy, hormone therapy, and targeted therapy. The goal of treatment is to remove or destroy the cancer cells, prevent the disease from spreading, and improve the person’s chances of survival and quality of life.

Regular breast self-exams, clinical breast exams by a healthcare professional, and mammograms are important for early detection and improved outcomes. It’s recommended that women begin having mammograms at age 40 or earlier if they have certain risk factors. Additionally, maintaining a healthy lifestyle, including regular exercise, a balanced diet, limiting alcohol consumption, and avoiding tobacco, may help reduce the risk of breast cancer.

If you have concerns about breast cancer or any related symptoms, it’s crucial to consult a healthcare professional for proper evaluation, diagnosis, and guidance.

TYPES OF BREAST CANCER

There are several different types of breast cancer, which can be classified based on various factors, including the specific cells involved, the way the cancer cells appear under a microscope, and the presence or absence of certain proteins. Here are some common types of breast cancer:

  1. Ductal Carcinoma in Situ (DCIS)
  2. Invasive Ductal Carcinoma (IDC)
  3. Invasive Lobular Carcinoma (ILC)
  4. Lobular Carcinoma in Situ (LCIS)
  5. Triple-Negative Breast Cancer
  6. Hormone Receptor-Positive Breast Cancer
  7. HER2-Positive Breast Cancer

It’s important to note that breast cancer is a complex disease, and each individual’s case can vary. The specific type of breast cancer, along with other factors like the stage and grade of the cancer, help determine the most appropriate treatment approach for a given patient. A healthcare professional can provide more detailed information and guide patients through diagnosis and treatment decisions.

 

SIGN AND SYMPTOMS OF BREAST CANCER

The signs and symptoms of breast cancer can vary among individuals, and some people may not experience any symptoms in the early stages. It’s important to note that many breast changes are not related to cancer but may still require medical evaluation. Here are some common signs and symptoms of breast cancer:

  1. Breast lump: A hard mass or lump in the breast or underarm area is one of the most common signs of breast cancer. 
  2. Changes in breast shape or size: Any noticeable changes in the shape or size of the breast, including swelling, asymmetry, or dimpling of the skin, should be evaluated.
  3. Breast pain or tenderness: While breast cancer typically does not cause pain, some individuals may experience breast pain or discomfort.
  4. Nipple changes: Such as inversion (when the nipple turns inward), redness, scaling, or discharge (other than breast milk) can be signs of breast cancer.
  5. Skin changes: Such as thickening, puckering, or dimpling, resembling an orange peel’s texture, may be a sign of breast cancer.
  6. Nipple discharge: Spontaneous nipple discharge that is bloody, clear, or another color, other than breast milk, may indicate breast cancer.
  7. Swollen lymph nodes: Swelling or lumps in the underarm or collarbone area may be a sign that breast cancer has spread to the lymph nodes.

 

CAUSES AND RISK FACTOR

The exact causes of breast cancer are not fully understood, but it is believed to be a combination of genetic, hormonal, environmental, and lifestyle factors. Here are some known risk factors and potential causes associated with breast cancer:

  1. Age: The majority of breast cancer cases occur in women over the age of 50.
  2. Gender: Breast cancer is much more common in women compared to men. However, men can also develop breast cancer, although it is relatively rare.
  3. Family history and genetic factors: Having a close relative, such as a mother, sister, or daughter, who has had breast cancer increases the risk. Certain inherited gene mutations, such as BRCA1 and BRCA2, significantly increase the risk of developing breast and ovarian cancer.
  4. Hormonal factors: Exposure to estrogen and progesterone over a long period of time can increase the risk of breast cancer. Factors that may contribute to increased hormone exposure include early onset of menstruation (before age 12), late menopause (after age 55), never having children, or having the first child after the age of 30.
  5. Personal history of breast abnormalities or previous breast cancer: Women who have had previous breast abnormalities, such as atypical hyperplasia or lobular carcinoma in situ (LCIS), have a higher risk of developing invasive breast cancer. 
  6. Dense breast tissue: Women with dense breast tissue, as seen on mammograms, have a higher risk of developing breast cancer.
  7. Lifestyle factors: Certain lifestyle choices and behaviors can impact breast cancer risk. These include excessive alcohol consumption, obesity or being overweight, lack of physical activity, and smoking.
  8. Radiation exposure: Previous radiation therapy to the chest area, particularly during adolescence or early adulthood, increases the risk of developing breast cancer later in life.

 

DIAGNOSIS

Breast cancer diagnosis typically involves a combination of clinical examinations, imaging tests, and biopsy procedures. Here are the common steps involved in diagnosing breast cancer:

  1. Clinical breast examination: A healthcare professional will perform a physical examination of the breasts, checking for any abnormalities, lumps, or changes in texture or shape.
  2. Imaging tests: Various imaging tests may be used to evaluate the breast tissue and detect any abnormalities. These tests include:
    • Mammogram
    • Ultrasound
    • Magnetic Resonance Imaging (MRI)
  3. Biopsy: If an abnormality is detected through a clinical examination or imaging tests, a biopsy will be performed to collect a sample of tissue for further analysis. There are different types of breast biopsies, including:
    • Fine-needle aspiration biopsy: A thin needle is used to extract cells from a suspicious area for examination.
    • Core needle biopsy: A slightly larger needle is used to remove a small cylinder of tissue for analysis.
    • Vacuum-assisted biopsy: A vacuum-powered device is used to remove multiple tissue samples through a single needle insertion.
    • Surgical biopsy: In some cases, a surgical procedure, such as a lumpectomy or excisional biopsy, may be necessary to remove a larger sample of tissue or the entire lump for examination.
  4. Pathology and laboratory analysis: The pathologist analyzes the tissue samples under a microscope to determine if cancer is present and provides information about the type, grade, and characteristics of the cancer cells.

Once a breast cancer diagnosis is confirmed, further tests may be done to determine the stage of the cancer and if it has spread to other parts of the body. This information helps guide treatment decisions.

It’s important to consult with a healthcare professional if you notice any breast abnormalities or have concerns about breast cancer. They can assess your individual situation, recommend appropriate tests, and guide you through the diagnosis process.

 

SCREENING

Breast cancer screening aims to detect breast cancer at an early stage, often before symptoms are present. Early detection allows for more effective treatment options and improved outcomes. Here are the main methods used for breast cancer screening:

  • Mammography: Mammograms are X-ray examinations of the breast tissue. Mammograms are the most common and widely recommended screening method for breast cancer. It is generally recommended that women start regular mammography screening between the ages of 40 and 50, although guidelines may vary depending on factors such as family history and individual risk factors.

 

  • Clinical Breast Examination (CBE): CBE is typically performed as part of a routine physical examination. However, its effectiveness as a standalone screening tool is still under debate, and its use may vary based on healthcare providers and guidelines.

 

  • Breast Self-Examination (BSE): Breast self-examination involves a person examining their own breasts regularly to detect any changes or abnormalities. While BSE used to be widely promoted, recent guidelines from organizations such as the American Cancer Society no longer recommend routine BSE as a screening method. However, it is still encouraged for individuals to be familiar with the normal look and feel of their breasts and report any changes to their healthcare provider.

It’s important to note that while screening can help with early detection, it also has limitations. Mammograms can occasionally miss some breast cancers, and false-positive results can lead to further testing and unnecessary anxiety. Additionally, screening mammograms may not be as effective in women with dense breast tissue. Therefore, it’s essential to discuss the benefits, limitations, and individualized screening recommendations with a healthcare professional based on personal risk factors, family history, and age.

Regular breast cancer screening, combined with awareness of changes in the breasts and prompt reporting of any concerns to a healthcare professional, plays a crucial role in the early detection and improved outcomes of breast cancer.

author

Aman k. Kashyap

I am a hard-working and driven medical student who isn't afraid to face any challenge. I'm passionate about my work . I would describe myself as an open and honest person who doesn't believe in misleading other people and tries to be fair in everything I do.

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  1. VAGINAL CANCER - says:

    […] important to remember that these symptoms can be caused by other non-cancerous conditions as well. However, if you experience any persistent symptoms or notice any unusual […]

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